November 05, 2025

The Dual-Phase PLLA Eye System: How AO Medical’s HOP+ and Skinbolic Gold Redefine Professional Eye Care

The Dual-Phase PLLA Eye System

How HOP+ Promoter Volumizing Eye & Lip Cream and Skinbolic Gold Eye Cream Work Together to Restore Structure and Radiance

The Skinbolic Gold Eye Cream has just launched on our website — and this one feels extra special. Already a long-time favorite in Korea, we worked closely with the Skinbolic team to reformulate it with Poly-L-Lactic Acid (PLLA) and adapt it for the U.S. professional market. The original formula was known for its radiance and elasticity, but our version brings it to another level — balancing structure and brightness, surface vitality and long-term collagen support.

It was originally formulated exclusively for us and went through months of testing, refinement, and shared trials with top Korean estheticians. The feedback was so remarkable that the Korean version was upgraded to match — and they absolutely love it. The formula has since gone viral again in Korea, celebrated for its radiance, elasticity, and luxurious texture.

Now let’s talk about our two PLLA-based eye creams:

1. HOP+ Promoter Volumizing Eye & Lip Cream

2. Skinbolic Gold Eye Cream

Both share the same collagen-supportive backbone yet serve distinct purposes. One rebuilds from within; the other perfects the surface. Used together, they complete each other — delivering both the foundation and the finish that define youthful, healthy skin.

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HOP+ Promoter Volumizing Eye & Lip Cream

Collagen & Circulation Renewal for Thin, Tired Skin

The HOP+ Eye & Lip Cream focuses on rebuilding strength and density where the skin is thinnest and most expressive. It’s powered by PLLA, the same biostimulatory polymer used in regenerative injectables, formulated in a cosmetic-grade dispersion for safe topical application.

PLLA stimulates fibroblast activity to gradually renew collagen and restore structure. It’s supported by a multi-peptide complex (Deca-, Octa-, Oligo-, and Pentapeptides) that signals matrix renewal while smoothing microtexture. Elderflower, Chamomile, Bilberry, and Açaí Extracts improve microcirculation and calm inflammation, while Shea Butter and Panthenol reinforce the barrier and lock in hydration.

The result: smoother, stronger, naturally plumped skin around the eyes and lips — revitalized from within. HOP+ is ideal for thinning or crepey skin, puffiness, and post-procedure recovery (microneedling, laser, or peels). Professionals often recommend it as a repair step for its restorative, barrier-rebuilding action.

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Skinbolic Gold Eye Cream

Radiance & Firming Refinement for the Outer Contour

In collaboration with the Skinbolic lab, we reimagined their iconic Gold Eye Cream — already a bestseller in Korea — for U.S. professional performance standards. The upgraded formula maintains its luminous texture but adds PLLA for deeper collagen conditioning.

It’s built around recombinant growth-factor peptides (sh-Oligopeptides, sh-Polypeptides) that signal epidermal renewal and DNA repair. Sodium DNA and Niacinamide improve tone and circulation, while Thiotaurine and Madecassoside deliver antioxidant protection. Tremella Mushroom Extract and Sodium Hyaluronate provide multi-layer hydration for a radiant, firm finish.

Light enough for daytime, rich enough for long-term repair — Skinbolic Gold Eye Cream is perfect for radiance, brightness, and firming without heaviness.

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How They Work in Synergy

The best results in eye care come from layering with intention, not duplication.

• HOP+ Eye & Lip Cream works from within, rebuilding collagen density, elasticity, and deep hydration.

• Skinbolic Gold Eye Cream perfects the surface — brightening tone, refining texture, and gently tightening the outer layers.

Together, they create a complete PLLA-based eye system bridging structure and glow — a multi-phase rejuvenation that supports skin on both biological and aesthetic levels.

How to Use

In Treatment

For professional use, apply HOP+ Eye & Lip Cream first, immediately following active modalities such as RF microneedling, fractional laser, LED, or oxygen therapy. Its PLLA and peptide base accelerates post-procedure collagen recovery and barrier repair.

Once absorbed, follow with Skinbolic Gold Eye Cream to enhance radiance, hydration, and surface smoothness. This sequence creates a rejuvenation cycle — collagen rebuilding from within and refinement on the surface.

At Home / Daily Use

Apply after toner, essence, and serum, and before moisturizer or SPF.

Use HOP+ first, allow 1–2 minutes for absorption, then layer Skinbolic Gold Eye Cream on top to seal in hydration and luminosity.

Clients with dry or mature skin can reapply either formula after moisturizer as a finishing step for added nourishment.

Both can be used day and night, or customized — HOP+ for volumizing and strengthening, Skinbolic Gold for refining and brightening.

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Which Treatment Is Best for Each Eye Cream

Each formula excels in a distinct phase of the treatment cycle:

• HOP+ Eye & Lip Cream — ideal for regenerative and reparative phases.

Use post-microneedling, RF, fractional laser, or peel. It restores barrier balance and supports collagen remodeling.

• Skinbolic Gold Eye Cream — best for radiance and maintenance phases.

Complements non-ablative lasers (IPL, Nd:YAG), LED, and oxygen facials. Locks in hydration, refines tone, and enhances post-treatment glow.

Used together, they bridge professional care and home care — HOP+ initiates repair; Skinbolic sustains brightness.

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Let’s Talk About Lips

The HOP+ Eye & Lip Cream also delivers outstanding lip benefits.

Unlike irritation-based plumpers, HOP+ strengthens lips from within through PLLA and peptide-driven collagen renewal.

Because lips lack oil glands and lose moisture easily, Panthenol, Shea Butter, and botanical antioxidants restore suppleness and prevent transepidermal water loss — leaving lips smooth, hydrated, and naturally plump over time.

Does Topical PLLA Really Work?

Yes — though not in the same way as injectables.

Injectable Poly-L-Lactic Acid (PLLA) works deep in the dermis, where it stimulates fibroblast activation through a controlled inflammatory process, gradually rebuilding collagen density and elasticity. Topical PLLA, in contrast, operates within the epidermis and superficial dermis — activating collagen-supportive pathways closer to the surface, improving hydration, texture, and dermal quality over time.

Formulated with micronized or nano-dispersed PLLA particles, topical systems apply the same regenerative principle through a noninvasive pathway. With consistent use, these particles can gradually interact with the epidermis and upper dermis, supporting fibroblast activity and promoting the skin’s natural collagen synthesis.

This process reinforces the extracellular matrix, improving elasticity, density, and smoothness. Over time, the skin appears firmer, more refined, and naturally plumped — not through artificial projection, but through its own collagen renewal and improved dermal structure.

Clinical studies have shown measurable improvements in elasticity, hydration, and surface resilience following regular topical PLLA application, supporting its role in long-term collagen induction. Even when combined with injectable PLLA, topical formulations continue to enhance results by maintaining surface-level collagen activity and reinforcing dermal integrity between treatments.

Whether used alone or within a professional regimen, topical PLLA delivers progressive, visible plumping and long-lasting improvement in texture, firmness, and overall vitality through natural collagen regeneration.

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References

1. Kim J., Lee S., et al. Efficacy of Topical Poly-L-Lactic Acid in Improving Skin Elasticity and Texture. Journal of Cosmetic Dermatology, 2022.

2. Ogawa M., Hattori T. Biostimulatory Effects of Nano-Dimensional Poly-L-Lactic Acid Particles in Human Dermal Fibroblasts. International Journal of Molecular Sciences, 2021.

3. Chang R., Park E., et al. Comparative Analysis of Injectable and Topical Poly-L-Lactic Acid: Mechanistic and Clinical Perspectives. Aesthetic Surgery Journal, 2023.

4. Yamada K., Mori D. Topical Application of Poly-L-Lactic Acid for Non-Invasive Collagen Induction Therapy. Dermatologic Therapy, 2020.

5. Lee S., Kang Y., et al. Mechanisms of Fibroblast Activation by Poly-L-Lactic Acid in Cutaneous Regeneration. Experimental Dermatology, 2021.

Collectively, these studies demonstrate that micronized and nano-dispersed PLLA particles can stimulate fibroblast activity and enhance dermal matrix organization without the invasiveness of injection. Consistent topical use has been shown to improve elasticity, hydration, and overall skin firmness.

When combined with peptides, antioxidants, and occlusive emollients — as in AO Medical’s HOP+ Promoter Eye & Lip Cream — PLLA acts as a collagen-conditioning system, progressively strengthening skin architecture and long-term resilience.

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The Professional Takeaway

Together, HOP+ Promoter Eye & Lip Cream and Skinbolic Gold Eye Cream form the AO Medical Dual-Phase PLLA Eye System — a professional-grade regimen that bridges structure and radiance.

• HOP+ rebuilds and reinforces from within.

• Skinbolic refines and brightens the surface.

Each product delivers measurable improvement on its own, but combined, they achieve layered rejuvenation that embodies AO Medical’s science and philosophy.

At AO Medical, we curate non-overlapping formulas that complement and elevate one another. Every product is selected for its clinical efficacy, integrity, and visible results. Our mission is not to expand endlessly — but to refine, redefine, and lead professional aesthetics with innovation that professionals trust.

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AO Medical Eye Care Collection Overview

All AO Medical eye creams are designed to work in harmony — they can be layered, cocktailed, or used day and night. Each formula enhances the others, creating synergy without redundancy.

Apply AO Medical eye treatments after toner, essence, and serum, and before moisturizer, creams, or SPF.

For extra nourishment, reapply after moisturizer as a sealing step — especially at night or in dry climates. Professionals may also cocktail or layer them in treatment, adjusting by phase: repair, brightening, firming, or volumizing.

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HOP+ Promoter Eye & Lip Cream

Purpose: Strengthens, volumizes, and restores structure where the skin is thinnest.

Key Actives: PLLA, Multi-Peptide Complex, Panthenol, Shea Butter, Elderflower, Chamomile, Bilberry, Açaí.

How It Works: PLLA renews collagen density; peptides stimulate matrix regeneration; antioxidants protect and soothe.

How to Use: Apply with metal applicator or fingertips. Use first when layering; can be used AM and PM or post-procedure.

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Skinbolic Gold Eye Cream

Purpose: Firms, brightens, and refines texture while enhancing circulation.

Key Actives: PLLA, sh-Oligopeptides, sh-Polypeptides, Sodium DNA, Niacinamide, Madecassoside, Tremella, Sodium Hyaluronate.

How It Works: Peptides renew surface texture; Sodium DNA and Niacinamide strengthen tone and radiance.

How to Use: Apply after serum or after HOP+ if layering; may also be used after moisturizer for a radiant finish.

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Hevatox Eye Cream

Purpose: Smooths and lifts with visible tightening for advanced aging or post-procedure care.

Key Actives: Botulinum-derived peptides, Retinaldehyde, Acetyl Hexapeptide-8, Adenosine, Ceramides.

How It Works: Relaxes fine lines, renews texture, and reinforces barrier elasticity.

How to Use: Use in the evening; layer after HOP+ or Skinbolic; avoid lash line if using retinoids.

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Dr. Esthé C-Tox Eye Cream

Purpose: Brightens, revitalizes, and reduces dark circles.

Key Actives: Vitamin C (Ascorbyl Glucoside), Niacinamide, Peptides, Caffeine, Hyaluronic Acid.

How It Works: Brightens pigmentation, improves circulation, and energizes tired eyes.

How to Use: Apply in the morning or pre-makeup; can be layered with HOP+ for combined radiance and plumpness.

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Together, these formulas form a comprehensive, professional-grade eye-care system — spanning collagen renewal, radiance correction, lifting, and tone improvement.

✨ Coming Soon: AO Medical PLLA Infusion Eye Patch Mask — designed to amplify in-clinic and home-care results through hydrogel-based PLLA and peptide infusion for next-level rejuvenation.

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At AO Medical, We Believe

True rejuvenation begins with structure and is perfected through radiance. The Dual-Phase PLLA Eye System embodies that philosophy — rebuilding from within while illuminating the surface, for results that are both clinically sound and beautifully natural.

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Frequently Asked Questions

How long does it take to see results?

The Dual-Phase PLLA Eye System is designed for gradual, cumulative improvement.

• Within 1 week — improved hydration and smoother texture.

• After 4 weeks — firmer tone and visibly brighter eye contours.

• After 8–12 weeks — a noticeable lift and enhanced resilience in the skin’s structure.

Consistency is key, and results continue to improve over time.

Can I use both if my skin is sensitive or post-procedure?

Yes. Both formulas are gentle and suitable once the surface has fully healed after treatments such as microneedling or laser.

For very sensitive or freshly treated skin, start with HOP+ alone for 5–7 days to rebuild the barrier. Once redness subsides, layer with Skinbolic to restore glow and hydration.

What makes these different from other eye creams?

Most eye creams focus solely on moisture or instant brightening.

The HOP+ and Skinbolic formulas are powered by Poly-L-Lactic Acid (PLLA), which works on a biological level to stimulate collagen renewal and strengthen the skin’s architecture.

Together, they bridge clinical and cosmetic care — treating both the foundation and the finish of healthy skin.

Are these pregnancy-safe or acne-prone skin friendly?

Both formulas are free of retinoids, exfoliating acids, and comedogenic ingredients. However, always consult an OB-GYN or dermatologist for personalized advice during pregnancy.

(Skinbolic contains nourishing emollients that may feel rich on very oily skin types; adjust usage as needed.)

Can I use these with my skincare devices?

Absolutely. Professionals often pair HOP+ with LED, microcurrent, or RF eye treatments for enhanced collagen support.

Apply HOP+ pre-device, then follow with Skinbolic post-treatment for cooling, firming, and radiance.

Where do they fit in my skincare routine?

Use them after toner and serum, before moisturizer or SPF.

Example: Cleanser → Toner → Serum → HOP+ Eye & Lip Cream → Skinbolic Gold Eye Cream → Moisturizer → SPF (AM).